Bulletin: First novel pain killer in 20 years gets FDA approval

Medical News Bulletin - Daily Medical News, Health News, Clinical Trials And Clinical Research, Medical Technology, Fitness And Nutrition News–In One Place

In a press release January 30th, the United States Food and Drug Administration announced that they have approved a novel non-opioid pain killer for acute pain. Acting FDA Center for Drug Evaluation and Research director Jacqueline Corrigan-Curay, J.D., M.D. explained the significance of this approval saying, ‘Today’s approval is an important public health milestone in […]

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Integrating Digital Health in Medical Education for Future Healthcare Training

Medical News Bulletin - Daily Medical News, Health News, Clinical Trials And Clinical Research, Medical Technology, Fitness And Nutrition News–In One Place

Digital health is transforming the medical landscape, offering unprecedented opportunities for enhanced education and patient care. As technology continues to evolve, the integration of digital tools into medical training is becoming increasingly crucial. This framework aims to standardize and globalize digital health education, preparing future healthcare professionals for a tech-driven world. The medical field is […]

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Zenocutuzumab exhibits efficacy in NRG1 fusion-positive cancers

Zenocutuzumab exhibited efficacy among patients with NRG1 fusion-positive cancers, according to phase 2 data published in The New England Journal of Medicine.
Nearly one-third of the cohort — which included patients with multiple tumor types — responded to therapy. Those with non-small cell lung cancer and pancreatic cancer derived the most benefit.
“We hoped and expected that zenocutuzumab would be effective in patients with NRG1-positive cancers; however, it was nonetheless very exciting to see these results,” Alison M. Schram, MD, gynecologic medical oncologist and

Right nomograms, instruments needed for ICL sizing

KOLOA, Hawaii — Measuring an eye for an ICL requires the right technology and formulas, according to a speaker at Hawaiian Eye 2025.
Helen K. Wu, MD, said the latest-generation EVO ICL (STAAR Surgical) has a lot of advantages but comes with challenges related to vault, which can be influenced by anatomy and the size of the ICL. Patients with low vault are at higher risk for complications such as cataract and decreased rotational stability, while patients with high vault are at higher risk for “pupillary block, endothelial cell loss, pigment dispersion, angle crowding and

WHO: Niger first African country to eliminate river blindness

Niger became the first African country to eliminate the parasitic infection onchocerciasis — also known as river blindness — and the fifth worldwide, according to WHO.
The declaration came after a decades-long effort that included vector control and mass drug administration to affected communities reduced the prevalence of the infection to nearly zero.
“Onchocerciasis has long caused immense human suffering,” Matshidiso Moeti, MD, MPH, WHO’s Regional Director for Africa, said in a press release. “It has also impeded the economic development of affected

Extreme heat may trigger thousands of hospitalizations in adults with Alzheimer’s

Older adults with Alzheimer’s disease and related dementias faced a greater risk for hospitalization after being continuously exposed to extreme heat, results from a cohort study showed.
The effects from continuous heat exposure appeared greater in certain diverse populations and climates, while the findings suggest that policymakers “should devise programs to mitigate these risks,” the researchers explained.
Scott W. Delaney, ScD, JD, MPH, a social and environmental epidemiologist at Harvard University, and colleagues explained that adults with Alzheimer’s disease and

Top in endocrinology: Metformin plus Mediterranean diet; lean mass loss with GLP-1s

A randomized controlled trial demonstrated a significantly reduced incidence of type 2 diabetes among individuals with metabolic syndrome who received daily metformin with or without a Mediterranean diet intervention.
Cumulative incidence of noncommunicable diseases appeared significantly lower among those who received metformin with or without a Mediterranean diet intervention.
“[Daily metformin] is effective in the prevention of diabetes, but not other NCDs, in people selected on the basis of metabolic syndrome,” Patrizia Pasanisi, MD, director of nutritional and metabolomic

Use of genetic variants to predict opioid use disorder risk may lead to inaccurate results

Candidate genetic variants included in a genetic risk algorithm may not meet standards of reasonable clinical efficacy in identifying opioid use disorder risk, according to a study published in JAMA Network Open.
“The FDA recently gave premarketing approval to an algorithm (AvertD, SOLVD Health) that incorporates 15 single nucleotide variants to predict opioid use disorder (OUD) risk,” Christal N. Davis, PhD, postdoctoral fellow at the Corporal Michael J. Crescenz Department of Veterans Affairs Medical Center in Philadelphia, and colleagues wrote. “The package insert for the

High-volume surgeons linked with lower revision rates after patellofemoral arthroplasty

Published results showed high-volume surgeons who performed more than five patellofemoral arthroplasty procedures per year had decreased rates of revision compared with low-volume surgeons.
In addition, high-volume surgeons were associated with decreased rates of complications and an increased likelihood of diagnosing and operating on patients with patellar disorders compared with low-volume surgeons.
“In the absence of national guidelines for treating patellofemoral joint osteoarthritis, patients may be unaware of the potential surgical options available to them unless they are offered them,”

Older adults with kidney disease face psychosocial barriers in transplant evaluation

Older adults with advanced kidney disease are often motivated to receive a transplant but may face emotional and psychosocial barriers during evaluation, according to a study.
“To promote broader and more equitable access to kidney transplant, many members of the transplant community have called for more proactive and inclusive approaches to transplant referral,” Catherine R. Butler, MD, MA, assistant professor of medicine in the division of nephrology in the department of medicine at the University of Washington in Seattle, wrote with colleagues. “While this approach may