A method to generate human airway epithelial organoids

Laboratory studies of lung tissue usually require the removal of large amounts of human or animal tissue. Now scientists from the University of Freiburg's Faculty of Medicine have succeeded in collaboration with American researchers in generating tiny quantities of lung tissue, so-called organoids, from just a few body cells in the lab. The tissue forms a three-dimensional structure as it develops, complete with the tiny hairs on the surface typical of lung tissue. These organoids can play an important part in future research on lung diseases, drug development, or personalized medicine. The researchers published their method in the online version of the American Journal of Physiology.
Laboratory studies of lung tissue usually require the removal of large amounts of human or animal tissue. Now scientists from the University of Freiburg’s Faculty of Medicine have succeeded in collaboration with American researchers in generating tiny quantities of lung tissue, so-called organoids, from just a few body cells in the lab. The tissue forms a three-dimensional structure as it develops, complete with the tiny hairs on the surface typical of lung tissue. These organoids can play an important part in future research on lung diseases, drug development, or personalized medicine. The researchers published their method in the online version of the American Journal of Physiology.