An emergency doctor and parent sorts through Covid vaccine options for kids under 5

How should parents look at the two possible Covid vaccine options for kids under 5? STAT spoke with Jeremy Faust, an emergency physician and dad who’s sorting through all of…

After months of delays and setbacks, there finally appears to be hope that there will be Covid-19 vaccine authorized for children under 5. Next month, the Food and Drug Administration plans to convene its vaccine advisory panel, known as VRBPAC, to review both Moderna and Pfizer-BioNTech’s shots for the youngest kids.

The vaccines are not identical: Moderna’s is two doses of 25 micrograms each, a quarter of Moderna’s adult dose. Its efficacy was between 37% and 51% in a trial against symptomatic Covid during the Omicron wave. Pfizer and BioNTech’s vaccine is three doses of 3 micrograms each, a tenth the adult dose. A preliminary efficacy figure based on only 10 cases seen in the trial was 80%, although that could change once more cases accrue.

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