An association between common antiepileptic drugs and incident Parkinson’s disease was found, researchers reported in JAMA Neurology.
Recent observational studies have established a temporal association between epilepsy and PD; however, the mechanism underlying the association is unclear, Daniel Belete, MBChB, of the preventive neurology unit at Queen Mary University of London, and colleagues wrote.
Belete and colleagues conducted a nested case-control study to investigate the association between antiepileptic drugs and incident PD.
The researchers obtained data from the UK Biobank in