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Irregular sleep cycles corresponded with increased risk for major adverse cardiovascular events like stroke or myocardial infarction, results from a population-based cohort study published in Journal of Epidemiology & Community Health suggested.
This increased risk remained even in irregular sleepers who met the recommended hours of sleep, the researchers added.
Irregular sleep has been connected to a wide variety of health and behavioral issues, ranging from worse grades in school among adolescents to the development of diabetes.
“However, it is unknown whether healthy sleep duration

BOSTON — Dupilumab reduced exacerbations and improved lung function in children with asthma, according to an abstract presented at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting.
“Over 80% of children with moderate to severe asthma that remains uncontrolled have evidence of elevated type 2 biomarkers,” Leonard B. Bacharier, MD, FACAAI, FAAAAI, Janie Robinson and John Moore Lee Chair in Pediatrics at Vanderbilt University Medical Center, said during his presentation. “In addition to that, a substantial proportion also have an allergic

Children of women prescribed antiseizure medications for epilepsy during pregnancy did not have worse neurodevelopmental outcomes by age 6 compared with children of women who did not receive them, according to new research.
“The effects of antiseizure medicines given during pregnancy are not known at later time points,” Adam Hartman, MD, program director at the NIH’s National Institute of Neurological Disorders and Stroke, told Healio in an email regarding the data published in JAMA Neurology. “This study fills that knowledge gap at a critical time in the child’s

Hundreds of millions of psychiatric disorders in the United States have been linked to childhood exposure of car exhaust from leaded gasoline, according to a recent study in the Journal of Child Psychology and Psychiatry.
The findings indicate that “lead has played a larger role in our mental health than previously thought,” Aaron Reuben, PhD, a postdoctoral scholar in neuropsychology at Duke University, told Healio.
According to Reuben and colleagues, lead exposure in most industrialized countries peaked from 1960 through 1990 due to the use of lead in gasoline, which was banned in

The FDA has granted rare pediatric disease designation to a type IA prodrug of dexamethasone that targets CD206+ macrophages for the treatment of systemic juvenile idiopathic arthritis flares, according to a press release from PIF Partners.
The proprietary investigational therapeutic, currently known as 101-PGC-005 or ‘005 (PIF Partners), is undergoing phase 3 clinical trials across nine centers in India for the treatment of autoimmune rheumatic diseases induced by COVID-19. Under the rare pediatric disease designation, PIF Partners is eligible to receive a priority review voucher upon

Two standard surgical procedures helped treat patients with trachomatous trichiasis, according to a study published in PLoS Neglected Tropical Diseases.
Emily W. Gower, PhD, of University of North Carolina at Chapel Hill, and colleagues said surgical outcomes are still an issue in countries where trachoma is endemic, so they explored which procedure worked best and if a different approach improved results.
“Some studies have reported postoperative trichiasis rates of 30% or higher for patients with trachomatous trichiasis following surgery, and repeat surgeries are more difficult,”

Regener-Eyes has launched a new preservative-free, multidose bottle with an improved design to prevent backflow and avoid bacterial contamination, according to a company press release.
“Following last week’s discussion with the FDA, we are confident that our new preservative-free bottles meet the standards for backflow prevention for preservative-free multidose bottles, and we are voluntarily recalling any remaining stock of the previous bottles,” a company spokesperson said in the release.
The new bottles, which were developed after consulting with physicians and industry

Greater amounts of screen time appeared to be associated with lower executive functioning among preschool-aged children, according to findings published in Academic Pediatrics.
According to previous research, screen time was associated with developmental delays and symptoms of anger in toddlers. Additionally, experts reported that toddlers who use tablets may be missing out on interactions with their parents.
WHO recommends a maximum of 1 hour of screen time per day for preschool-aged children, according to Caroline Fitzpatrick, PhD, associate professor in the department of preschool and

Greater exposure to particulate matter in the air may be linked to longer duration of long COVID symptoms, a population-based cohort analysis published in Environmental Health Perspectives showed.
The findings build upon previous literature on environmental pollutants, COVID-19 and long COVID, with the risk of long COVID remaining significant even after declining rates during the pandemic.
“We previously found that air pollution exposure is linked to a higher risk of severe COVID-19 and a lower vaccine response, but there are very few studies on long COVID and the environment,”