Novel cyclic peptide antagonist can be a promising therapeutic approach for MASH
The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.
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Advances in organ preservation techniques and future prospects
A review article published in Engineering delves into the crucial field of organ preservation, exploring its history, current techniques, and future prospects.
Breakthrough peptide inhibitor effective against multiple SARS-CoV-2 variants
SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors.
Fighting cancer, inflammation and unlocking dementia diagnostics
In recognition of their discovery of one of our immune system’s foundations, physician Andrea Ablasser, virologist Glen Barber and biochemist Zhijian J. Chen will be awarded the Paul Ehrlich and Ludwig Darmstaedter Prize 2025, endowed with €120,000, in Frankfurt’s Paulskirche today.
Optimized fermentation process unlocks anti-aging potential of tapuy lees
Filipino researchers have found a way to optimize the traditional procedure for making Philippine rice wine or "tapuy" to produce a potential superfood rich in anti-aging compounds and antioxidants.
STAT+: U.K. plan to require drugmakers to pay higher rebates draws criticism from industry group
The U.K. government proposes raising mandatory drug rebates paid by drug companies to bolster the National Health Service. U.K. pharma is not happy.
Opinion: I’m head of an NGO in Kenya. The shutoff of USAID support has been devastating
“There is a pervasive sense of fear — of losing access to critical health care services and of livelihoods lost,” CFK Africa Executive Director Jeffrey Okoro writes about the end…
Key Factors Influencing the Outcome of Mesothelioma Settlements
Many people who have struggled with mesothelioma have sought out a settlement somewhere down the line. This has a lot to do with the fact that mesothelioma can stem from conditions people aren’t aware of. Whether it’s from their occupation or where they live, mesothelioma gained notoriety due to its relation to asbestos. Settlement outcomes […]
The post Key Factors Influencing the Outcome of Mesothelioma Settlements appeared first on Medical News Bulletin.
Gilead encouraged by data on once-yearly lenacapavir for HIV prevention
SAN FRANCISCO — New data suggest that lenacapavir delivered just once per year could be as effective for HIV prevention as the twice-yearly injections already under review by the FDA.
Gilead Sciences presented data from a phase 1 study of once-a-year lenacapavir for HIV PrEP at the Conference on Retroviruses and Opportunistic Infections and published the results simultaneously in The Lancet.
The study showed that either of the two new formulations of the drug could be effective, allowing people to receive the drug just once per year instead of twice.
“What we found is that the ...
Obesity and diabetes: Understanding the global surge and how to solve it
The prevalence of obesity and diabetes has grown worldwide, presenting notable challenges to public health and health care systems.
Gaining a comprehensive understanding of the causes and implications of these conditions is essential for developing effective prevention and management strategies.
The global rise in obesity and diabetes can be attributed to several interconnected factors:
First among them are dietary shifts in which modern diets are dominated by ultraprocessed foods high in refined sugars, unhealthy fats, large portion sizes and empty calories, fueling the obesity and diabetes