Biomarkers that predict ICS, LAMA response may differ in adults vs adolescents with asthma

Biomarkers that predict response to inhaled corticosteroid or long-acting muscarinic antagonist treatment may differ between adults and adolescents with uncontrolled mild persistent asthma, researchers reported.
“In the combined study population of adults and adolescents enrolled in the SIENA trial, we previously reported that blood eosinophil levels and the fractional exhaled nitric oxide each predicted response to inhaled corticosteroids for the composite outcome but not response to LAMA,” Jerry A. Krishnan, MD, PhD, associate vice chancellor for population health sciences and

Biomarkers that predict response to inhaled corticosteroid or long-acting muscarinic antagonist treatment may differ between adults and adolescents with uncontrolled mild persistent asthma, researchers reported.
“In the combined study population of adults and adolescents enrolled in the SIENA trial, we previously reported that blood eosinophil levels and the fractional exhaled nitric oxide each predicted response to inhaled corticosteroids for the composite outcome but not response to LAMA,” Jerry A. Krishnan, MD, PhD, associate vice chancellor for population health sciences and