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Review of meeting abstracts shows toxicity reporting inconsistent, incomplete

Toxicity reporting in certain abstracts presented in recent years at ASH Annual Meeting and Exposition appeared inconsistent and incomplete, according to a systematic review.
In many cases, toxicity reporting was absent from abstracts, results showed.
Researchers — who reviewed abstracts that highlighted phase 3 clinical trials in acute leukemia presented at ASH from 2017 to 2012 — often observed “formal toxicity minimization” and subjective terms to minimize toxicity.
Healio spoke with Lisa K. Hicks, MD, MSc, associate professor at University of Toronto and hematologist

CeramTec appoints Sternberg as new president medical

CeramTec has announced Katrin Sternberg, PhD, as new president medical, according to a company press release.
On Feb. 1, Sternberg assumed the position of president medical from Hadi Saleh, PhD, who will remain CEO of the company. Sternberg, who previously served as a member of the executive board for B. Braun Aesculap, will also join the management board of CeramTec, according to the release.
“As we continue to advance CeramTec’s footprint as a leading global [medical technology] platform, we firmly believe that putting a dedicated leadership resource in place for our medical

FDA clears IND application to treat excessive stool frequency in patients with J-pouches

The FDA cleared the investigational new drug application for ExeGi Pharma LLC’s, EXE-346, a live biotherapeutic biologic drug intended for patients with ileal pouch-anal anastomosis who experience excessive stool frequency.
Patients who undergo ileal pouch-anal anastomosis – or J-pouch procedure – may later experience excessive stool frequency of six or more times daily, with nighttime stool frequency also reported as a common problem. With no currently approved therapies to manage this condition, the FDA clearance will allow ExeGi Pharma to start enrollment for a clinical

Young adults with depression, poor mental health at greater CVD risk

Depression and high quantity of poor mental health days are independently associated with premature CVD and suboptimal CV health in young people, according to a study published in the Journal of the American Heart Association.
“The relationship between depression and heart disease is a two-way street. Depression increases your risk of heart issues, and those with heart disease experience depression,” Yaa A. Kwapong, MD, MPH, a postdoctoral research fellow at Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, said in a press release. “Our study

Global study highlights wide disparity in COVID-19 vaccination among older adults

Although roughly 77% of older adults globally have been vaccinated against COVID-19, researchers found wide disparities in vaccination rates based on income levels.
According to the findings, 90% of older adults in high-income nations have been vaccinated compared with roughly one-third in low-income nations.
In 2022, WHO set a goal of vaccinating 100% of populations at increased risk for SARS-CoV-2, and although more wealthy countries have managed to approach that goal, the study published in MMWR suggests the rest of the world lags behind.
Among these priority populations is older adults, who

VIDEO: Complying with Americans with Disabilities Act benefits practice websites

In this Healio Video Perspective, Cynthia A. Matossian, MD, FACS, and David Evans, PhD, MBA, discuss how practice owners can ensure that their websites are meeting the requirements of the Americans with Disabilities Act.
Additionally, striving to meet these requirements offers specialists opportunities to make their websites easier to use and more efficient for patients.
“The bottom line is ADA compliance actually improves the user experience,” Evans said. “The things you’re going to do to meet ADA compliance are going to make your website easier to use, so why not kill

Neighborhood walkability linked to risk of gestational diabetes

A new study by scientists in the Columbia University Mailman School of Public Health's Built Environment and Health Research Group finds that higher neighborhood walkability is associated with lower risk of gestational diabetes (GD). The results of the study are published in the peer-reviewed journal Paediatric and Perinatal Epidemiology.