Childhood acute leukemia survivors with Down syndrome at higher risk for late mortality

Childhood acute leukemia survivors with Down syndrome had increased risk for late mortality not attributable to cardiac- or subsequent malignant neoplasm-associated late effects, according to study results published in Cancer.
“Although [childhood leukemia survivors] with Down syndrome were at greater risk for late effects such as hearing loss and cataracts compared with [survivors who did not have Down syndrome], this risk was not greater than that seen among Down syndrome controls, suggesting that these morbidities are related to the underlying Down syndrome and not leukemia treatment,”

Childhood acute leukemia survivors with Down syndrome had increased risk for late mortality not attributable to cardiac- or subsequent malignant neoplasm-associated late effects, according to study results published in Cancer.
“Although [childhood leukemia survivors] with Down syndrome were at greater risk for late effects such as hearing loss and cataracts compared with [survivors who did not have Down syndrome], this risk was not greater than that seen among Down syndrome controls, suggesting that these morbidities are related to the underlying Down syndrome and not leukemia treatment,”