Researchers are calling for the creation of a comprehensive framework to address current barriers to xenotransplantation in clinical practice, including issues of rejection, infection, legal regulations, informed consent and animal rights.
In a state-of-the-art review published in JACC: Basic to Translational Science, researchers noted the heightened interest in xenotransplantation after reports of the first human to receive the heart of a genetically modified pig in January, a moment that came after decades of failure in experimental animal models.
“We believe that if the regulatory,