Patients with antibody deficiencies demonstrated reduced immunogenicity following vaccination against the SARS-CoV-2 virus, according to a study published in Journal of Clinical Immunology.
These findings demonstrate the ongoing risk that the virus presents these patients, Adrian M. Shields, MBBS, MRCP, PhD, clinical lecturer at University of Birmingham Institute of Immunology and Immunotherapy in the United Kingdom, and colleagues wrote.
The COVID-19 in patients with antibody deficiency (COV-AD) study began recruiting 320 patients (median age, 58.5 years; 40% men) aged 18 years and older from