Laura Boekel and colleagues pooled data from two large ongoing prospective cohort studies and analyzed post-vaccination serum samples for evidence of breakthrough infection. They report that the incidence of breakthrough infections was comparable between patients taking immunosuppressants and controls. Hospitalization was required in similar proportions in both groups—and in general hospitalized cases were older, and had more comorbidities compared with non-hospitalized cases.
COVID breakthrough infections: RMD not necessarily a risk group for severe COVID-19
Laura Boekel and colleagues pooled data from two large ongoing prospective cohort studies and analyzed post-vaccination serum samples for evidence of breakthrough infection. They report that the incidence of breakthrough infections was comparable between patients taking immunosuppressants and controls. Hospitalization was required in similar proportions in both groups—and in general hospitalized cases were older, and had more comorbidities compared with non-hospitalized cases.