Delgocitinib cream demonstrated superiority to alitretinoin capsules in the treatment of severe chronic hand eczema, LEO Pharma announced in a press release.
Alitretinoin (Panretin, Concordia) is the only treatment currently approved to specifically treat severe chronic hand eczema (CHE) in patients who do not respond to topical corticosteroids. Delgocitinib cream (LEO Pharma), on the other hand, is an investigational, topical pan-Janus kinase (JAK) inhibitor.
In a phase 3 study from LEO Pharma, the efficacy and safety of delgocitinib cream was compared with alitretinoin capsules for the