Dextromethorphan-bupropion effective in improving symptoms of major depressive disorder

Dextromethorphan-bupropion significantly improved symptoms for those with major depressive disorder compared with bupropion alone and produced minimal adverse effects, according to a study published in American Journal of Psychiatry.
“Major depressive disorder is a prevalent and disabling condition, and it is the leading cause of disability worldwide,” Herriot Tabuteau, MD, founder and CEO of Axsome Therapeutics, and colleagues wrote. “A tablet (AXS-05) combining dextromethorphan and buproprion has been formulated ... for the treatment of major depression.”
Tabuteau and

Dextromethorphan-bupropion significantly improved symptoms for those with major depressive disorder compared with bupropion alone and produced minimal adverse effects, according to a study published in American Journal of Psychiatry.
“Major depressive disorder is a prevalent and disabling condition, and it is the leading cause of disability worldwide,” Herriot Tabuteau, MD, founder and CEO of Axsome Therapeutics, and colleagues wrote. “A tablet (AXS-05) combining dextromethorphan and buproprion has been formulated … for the treatment of major depression.”
Tabuteau and