Diabetes risk increased among people with HIV on INSTI-based ART

People with HIV who are on ART regimens using integrase strand transfer inhibitors are at an increased risk for diabetes or hyperglycemia within the first 6 months of treatment, researchers found.
“We had noted in clinic that a handful of patients who started integrase strand transfer inhibitors (INSTIs) developed diabetes or lost control of previously well-controlled diabetes,” Jane A. O’Halloran, MD, PhD, assistant professor of medicine at the Washington University School of Medicine in St. Louis, told Healio. “This, coupled with evidence that INSTIs are associated

People with HIV who are on ART regimens using integrase strand transfer inhibitors are at an increased risk for diabetes or hyperglycemia within the first 6 months of treatment, researchers found.
“We had noted in clinic that a handful of patients who started integrase strand transfer inhibitors (INSTIs) developed diabetes or lost control of previously well-controlled diabetes,” Jane A. O’Halloran, MD, PhD, assistant professor of medicine at the Washington University School of Medicine in St. Louis, told Healio. “This, coupled with evidence that INSTIs are associated