Differences in neurodevelopmental maturation of structural brain networks leave certain adolescents at high genetic risk for bipolar disorder, according to an Australian study published in the American Journal of Psychiatry.
“Recent structural and functional imaging studies of bipolar disorder have revealed connectivity disturbances centered on key emotional and cognitive hubs,” Gloria Roberts, PhD, of the school of psychiatry at the University of New South Wales, and colleagues wrote. “Such disconnections produce a loss of integration between emotional circuitry and