Whole-exome sequencing identified carriers of predisposition genes for hereditary breast and ovarian cancer or Lynch syndrome who, under current guidelines, would not have qualified for genetic testing, according to study results.
The findings, presented at American Association for Cancer Research Annual Meeting, highlighted the need for wide genomic screening for inherited autosomal dominant cancer predisposition conditions, dubbed CDC Tier 1 genetic conditions, for which early identification and intervention could have a positive impact on public health, researchers noted.
There has been a