According to published results, extended oral antibiotic prophylaxis after aseptic revision total knee arthroplasty yielded a sevenfold reduction in 90-day infection risk.
Brandon R. Bukowski, MD, and colleagues at Mayo Clinic, Rochester retrospectively compared outcomes of aseptic revision TKA in 267 patients who received extended oral antibiotic (EOA) prophylaxis with cases of aseptic revision TKA in 637 patients who received no EOAs. According to the study, mean duration of EOA therapy was 11 days after surgery. Outcome measures included cumulative probability of infection, periprosthetic