
The FDA has granted priority review to Reata Pharmaceuticals Inc.’s new drug application for omaveloxolone to treat patients with Friedreich’s ataxia.
According to a company press release, the NDA is supported by positive safety and efficacy data from the MOXIe part 2 trial as well as supporting data from MOXIe part 1 and MOXIe extension trials.
Omaveloxolone (RTA 408, Reata), an oral, once-daily anti-inflammatory therapeutic, received fast track designation in November 2021 and rare pediatric disease designation in May 2022. The priority review designation shortens the FDA’s