First proposed definition for disease modification in lupus focuses on disease activity

The first proposed definition for disease modification in systemic lupus erythematosus, including lupus nephritis, requires “minimizing” disease activity with few treatment-associated toxicities, while slowing organ damage progression.
The proposed definition is the product of a review published in Lupus Science & Medicine. It is the first published article to put forth a definition of disease modification in SLE, including lupus nephritis, according to a statement and white paper from GlaxoSmithKline, which funded the review.
“No widely accepted definition of disease