In this issue of Healio Psoriatic Disease, we focus on the genetics of psoriasis, a daunting topic for sure! Psoriasis is one of the most heritable of complex genetic trait diseases. Over 65 susceptibility loci have been identified, but 75% of psoriasis heritability is not explained by currently known variants, suggesting there is much more to learn.
So, what does a clinician need to know about the genetics of psoriasis? Plenty! I will summarize some key findings that I find very helpful in my clinical practice.
First, as I am sure you will agree, a common question that patients with psoriasis