High-risk women need higher levels of plasma tenofovir for HIV protection

Women at high risk for HIV need higher levels of plasma tenofovir to prevent infection compared with men, according to data from the largest HIV pharmacokinetics database to date.
“While daily tenofovir-based PrEP has shown efficacy in decreasing incident HIV infections in populations at risk for HIV infection, the protective level of tenofovir associated with prevention is not known,” Radojka M. Savic, PhD, professor of bioengineering at the University of California San Francisco, told Healio.
Savic said adherence to PrEP is “imperfect and varies between populations, and

Women at high risk for HIV need higher levels of plasma tenofovir to prevent infection compared with men, according to data from the largest HIV pharmacokinetics database to date.
“While daily tenofovir-based PrEP has shown efficacy in decreasing incident HIV infections in populations at risk for HIV infection, the protective level of tenofovir associated with prevention is not known,” Radojka M. Savic, PhD, professor of bioengineering at the University of California San Francisco, told Healio.
Savic said adherence to PrEP is “imperfect and varies between populations, and