IgG4 may be ‘innocent bystander’ in IgG4 disease

DESTIN, Fla. — The role of IgG4 itself in IgG4 disease remains unclear, one of the many unexplained components of the condition, according to data presented at the Congress of Clinical Rheumatology East.
“We really do not understand the role of IgG4 in this disease,” Zachary S. Wallace, MD, MSc, of Massachusetts General Hospital, said in his presentation. “It may just be an innocent bystander. We are still trying to understand better what is driving the symptoms in these patients.”
Another complicating factor is that serum IgG4 concentrations are not necessarily

DESTIN, Fla. — The role of IgG4 itself in IgG4 disease remains unclear, one of the many unexplained components of the condition, according to data presented at the Congress of Clinical Rheumatology East.
“We really do not understand the role of IgG4 in this disease,” Zachary S. Wallace, MD, MSc, of Massachusetts General Hospital, said in his presentation. “It may just be an innocent bystander. We are still trying to understand better what is driving the symptoms in these patients.”
Another complicating factor is that serum IgG4 concentrations are not necessarily