Inhaled hypertonic saline treatment for 48 weeks led to positive effects on structural lung changes in young children with cystic fibrosis compared with isotonic saline, researchers reported in The Lancet Respiratory Medicine.
Harm A.W.M. Tiddens, MD, professor in the department of pediatrics/respiratory medicine at Sophia Children’s Hospital in Rotterdam, the Netherlands, and colleagues conducted the SHIP-CT trial to evaluate the effects of inhaled hypertonic saline on chest CT imaging in young children with cystic fibrosis. In the prior SHIP study, inhaled hypertonic saline improved