Microvascular function affected by HF correlated to cognitive impairment

Researchers reported that HF was independently prognostic of both cardiac and cerebral microvascular dysfunction predictive of impaired cognitive function.
The data were published in Circulation: Heart Failure.
“Although the underlying pathophysiology of HF is heterogenous and remains incompletely understood, many overlapping pathophysiologic mechanisms have been proposed for the HF-associated development of cognitive impairment, including chronic cerebral hypoperfusion or decreased cerebrovascular reactivity through endothelial dysfunction, arterial hypertension, and systemic inflammation,”

Researchers reported that HF was independently prognostic of both cardiac and cerebral microvascular dysfunction predictive of impaired cognitive function.
The data were published in Circulation: Heart Failure.
“Although the underlying pathophysiology of HF is heterogenous and remains incompletely understood, many overlapping pathophysiologic mechanisms have been proposed for the HF-associated development of cognitive impairment, including chronic cerebral hypoperfusion or decreased cerebrovascular reactivity through endothelial dysfunction, arterial hypertension, and systemic inflammation,”