Novel Isotretinoin Ointment For Congenital Ichthyosis Shows PromiseTMB-001 is a topical isotretinoin formulation that uses a patented 'IPEG' technology isotretinoin delivery system. Medscape Medical Newsadminmarzo 28, 2022Uncategorized TMB-001 is a topical isotretinoin formulation that uses a patented ‘IPEG’ technology isotretinoin delivery system. Medscape Medical News