Comorbid peripheral artery disease is a significant risk factor for adverse events for patients with acute MI with cardiogenic shock, including worse limb outcomes and poorer short- and long-term survival compared with those without PAD.
In an analysis of more than 70,000 Medicare beneficiaries, researchers also found that patients with acute MI, cardiogenic shock and comorbid PAD were less likely to receive mechanical circulatory support; those who did had increased mortality, lower extremity revascularization and amputation rates.
“Presentation with acute MI and cardiogenic shock is