Nearly 40% of adults with type 1 diabetes not diagnosed until after age 30 years

Almost four in 10 adults with type 1 diabetes were not diagnosed until after the age of 30 years, according to a recently published study.
“Adult-onset type 1 diabetes is frequently misdiagnosed as type 2 diabetes, leading to inappropriate care,” Michael Fang, PhD, MHS, an assistant professor of epidemiology at John Hopkins Bloomberg School of Public Health, and colleagues wrote in the Annals of Internal Medicine. “Emerging data suggest that up to 62% of type 1 diabetes cases develop after age 20 years.”
However, they pointed out that prior studies have been done on only

Biomarker tracks depression recovery after deep brain stimulation

A small study of patients with treatment-resistant depression identified a brain-based biomarker of recovery following deep brain stimulation of the subcallosal cingulate.
The study, published in Nature and supported by the NIH, found that local field potential changes in the subcallosal cingulate correlated with a patient’s clinical state. The finding addresses a lack of objective benchmarks in the path to recovery after deep brain stimulation (DBS), which usually requires trial-and-error therapeutic adjustments, researchers wrote.
“This study also gives us an amazing scientific

CDC: Around 1 in 100 US children have had long COVID

As of last year, around one in 10 children in the United States had ever had long COVID, according to survey findings reported by the CDC’s National Center for Health Statistics.
The finding is based on 7,464 interviews conducted for the 2022 National Health Interview Survey Sample - Child, mostly by telephone.
According to the results, in 2022, 1.3% of children in the U.S. reported ever having long COVID, defined as symptoms lasting 3 months or longer that were not present prior to having COVID-19.
Among the respondents, 0.5% of children had long COVID at the time of the interview.

Patients with intra-articular mineralization have twice the odds of frequent knee pain

Patients with intra-articular mineralization demonstrate a two-times higher likelihood of having frequent knee pain, as well as more intermittent or constant pain, according to data published in Arthritis & Rheumatology.
“Intra-articular (IA) crystal deposition is common in knee [osteoarthritis (OA)], yet its clinical significance remains unclear,” Jean W. Liew, MD, assistant professor of medicine and rheumatologist at Boston University, and colleagues wrote. “Crystals that can deposit intra-articularly in OA include calcium pyrophosphate (CPP) and basic calcium phosphate

Elevated levels of fibroblast growth factor 23 may be linked with heart failure risk

Elevated levels of fibroblast growth factor 23 may be associated with an increased risk for heart failure in adults with chronic kidney disease, according to a recently published study.
“Heart failure is a prominent comorbidity among patients with chronic kidney disease,” Alexander S. Leidner, MD, of the Northwestern University Feinberg School of Medicine in Chicago, Illinois, and colleagues, wrote in the study. “We examined the associations between baseline [fibroblast growth factor 23 (FGF23)] and first [heart failure (HF)] hospitalization across HF subtypes among