A Nobel Prize-worthy question: How do we sense heat, cold, touch?

For centuries, understanding the basis for how we detect, process and react to light, sound, temperature, pressure and other environmental signals has been a scientific focus. Science has advanced, and new understanding at the cellular level of ion channels—which are fundamental to these sensations and our bodies' functions—has contributed to important advancements, including the development of new and effective drugs. An indication of the significance of this science and research came with the awarding of the 2021 Nobel Prize in Physiology or Medicine, which honored the discovery of the fundamental ion-channel sensors for temperature and pressure.