Accelerating pathogen identification in infants and children with bloodstream infections

A collaborative team led by researchers from Great Ormond Street Institute of Child Health (GOSH), London and including researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University and BOA Biomedical in Cambridge has re-engineered the process of microbial pathogen identification in blood samples from pediatric sepsis patients using the Wyss Institute's FcMBL broad-spectrum pathogen capture technology. The advance enables accurate pathogen detection with a combination of unprecedented sensitivity and speed, and could significantly improve clinical outcomes for pediatric and older patients with bloodstream infections (BSIs) and sepsis. The findings were published in PLoS ONE.

Respiratory Syncytial Virus (RSV) 

Medical News Bulletin - Daily Medical News, Health News, Clinical Trials And Clinical Research, Medical Technology, Fitness And Nutrition News–In One Place

Increasing numbers of infants and children are missing school and other critical developmental activities because of the current triple threat. The triple threat comprises COVID-19, the seasonal flu, and a lesser-known virus. This lesser-known virus is the respiratory syncytial virus (RSV) and used to be a yearly virus floating around. RSV and its associated RSV […]

The post Respiratory Syncytial Virus (RSV)  appeared first on Medical News Bulletin.

Ankle replacement, fusion yield similar clinical scores for patients with end-stage OA

Total ankle replacement and ankle fusion for patients with end-stage ankle osteoarthritis had similar clinical outcome scores at 52 weeks after surgery, according to published results.
Andrew J. Goldberg, MBBS, and colleagues randomly assigned 282 patients (mean age of 67.9 years) with end-stage ankle OA to receive either total ankle replacement (TAR; n = 138) or ankle fusion (n = 144) from March 6, 2015, to Jan. 10, 2019. The primary outcome measure was the Manchester-Oxford Foot Questionnaire walking/standing (MOXFQ-W/S) domain score from baseline to 52 weeks postoperatively.
At 52 weeks, the

Increases in youth suicide linked to mental health worker shortage

A study found an association between shortages in mental health workers and increases in youth suicide rates, according to findings published in JAMA Pediatrics.
Co-author Jennifer A. Hoffmann, MD, MS, an attending physician in the division of emergency medicine at Lurie Children’s Hospital of Chicago and assistant professor of pediatrics at Northwestern University Feinberg School of Medicine, told Healio that “swift action is needed to support youth mental health,” amid what the AAP and other groups have called a “national emergency” in pediatric mental health.

Fatty pancreas increases diabetes risk, but may be reversible with weight loss

Adults with an elevated level of pancreatic fat have higher risk for developing incident diabetes, but weight loss may be able to lower diabetes risk by reducing fat levels and increasing pancreatic volume, according to a presenter.
“Fatty pancreas is associated with insulin resistance and increased insulin secretion cross-sectionally in nondiabetic individuals and is more prevalent in type 2 diabetes,” Richard E. Pratley, MD, the Samuel E. Crockett Chair in Diabetes Research, medical director of AdventHealth Diabetes Institute and a Healio | Endocrine Today Co-editor, said during

AGA ‘applauds FDA’ for first approved fecal microbiota biotherapeutic

Following FDA approval of the first fecal microbiota biotherapeutics for recurrent Clostridoides difficile, the American Gastroenterological Association summarized what this means for gastroenterologists and patients going forward.
Aside from this approval, a press release noted the largest change to previous guidance is that the FDA will now require stool banks that provide fecal microbiota therapy products (FMT) to comply with investigational new drug requirements. In the meantime, health care professionals can continue use of appropriately screened donated stool for patients with recurrent

‘No time to waste’: Implement guideline-recommended HF therapies simultaneously

The benefits of HF medications are additive and incremental and provide similar benefits to patients with ischemic and nonischemic etiologies when initiated simultaneously, according to a speaker.
Despite treatment advances in HF, many eligible patients are not receiving one or more evidence-based, guideline-recommended HF therapies, Gregg C. Fonarow, MD, FACC, FAHA, FHFSA, director of the Ahmanson-UCLA Cardiomyopathy Center, co-director of the UCLA Preventive Cardiology Program, co-chief of the division of cardiology at UCLA and the Eliot Corday Chair in Cardiovascular Medicine and Science,