Patients with asthma, chronic rhinosinusitis with nasal polyps and atopic dermatitis experienced transient increases in eosinophil counts following treatment with dupilumab, according to study results.
However, these increases mostly were not associated with clinical symptoms or sequalae, nor did they have any observable impact on treatment efficacy, Michael E. Wechsler, MD, MMSc, a pulmonologist at National Jewish Health in Denver, and colleagues wrote in the study, published in The Journal of Allergy and Clinical Immunology: In Practice.
The researchers conducted a post-hoc analysis of 11