Treatment with tenecteplase in an Australian mobile stroke unit was safe and resulted in improved outcomes compared with alteplase, according to a study published in The Lancet Neurology.
“Several clinical trials have suggested benefit of tenecteplase vs. alteplase, but none of these trials were performed in the prehospital setting,” Andrew Bivard, PhD, of the Melbourne Brain Centre at the University of Melbourne Royal Melbourne Hospital in Australia, and colleagues wrote.
Bivard and fellow researchers sought to test the hypothesis that tenecteplase, given to ischemic stroke