Preliminary results of an ongoing study on topography-guided customized corneal cross-linking indicate that the high-oxygen epi-on protocol leads to less pain and faster improvement as compared with the epi-off procedure in room air.
“We have shown previously that customized remodeled vision (CuRV) CXL has refractive advantages over conventional CXL in keratoconus. In an ongoing study, we are now comparing the results of one eye treated with epi-on CuRV in high oxygen and one eye with epi-off CuRV in room air in 45 patients,” Anders Behndig, MD, PhD, said at the virtual European