Since March 2020, the SARS-CoV-2 virus, the cause of coronavirus disease 2019 (COVID-19), has infected more than 460 million people worldwide. The vast majority of people who recover from infection demonstrate long-lasting immune memory of the virus. Little is known, however, about how this immune memory alters responses to SARS-CoV-2 mRNA vaccines, despite possible impacts on public health guidelines for vaccination.
Prior COVID-19 infection linked to robust, accelerated immune response after first vaccine dose
Since March 2020, the SARS-CoV-2 virus, the cause of coronavirus disease 2019 (COVID-19), has infected more than 460 million people worldwide. The vast majority of people who recover from infection demonstrate long-lasting immune memory of the virus. Little is known, however, about how this immune memory alters responses to SARS-CoV-2 mRNA vaccines, despite possible impacts on public health guidelines for vaccination.