Recurrent ductal carcinoma in situ tumors often genetically distinct from primary lesion

A substantial portion of ductal carcinoma in situ recurrences did not appear genetically related to their primary lesions, according to study findings presented at American Association for Cancer Research Annual Meeting.
De novo tumors with distinct genetic alterations accounted for nearly two in 10 recurrences, the detailed molecular analysis showed.
Results call into question whether a tumor-intrinsic biomarker alone could sufficiently predict recurrences among patients with ductal carcinoma in situ, Tanjina Kader, PhD, postdoctoral researcher at Peter MacCallum Cancer Centre in Australia,

A substantial portion of ductal carcinoma in situ recurrences did not appear genetically related to their primary lesions, according to study findings presented at American Association for Cancer Research Annual Meeting.
De novo tumors with distinct genetic alterations accounted for nearly two in 10 recurrences, the detailed molecular analysis showed.
Results call into question whether a tumor-intrinsic biomarker alone could sufficiently predict recurrences among patients with ductal carcinoma in situ, Tanjina Kader, PhD, postdoctoral researcher at Peter MacCallum Cancer Centre in Australia,