
High efficacy and acceptability were demonstrated in both on-label and off-label medications for fibromyalgia, reinforcing the value of symptom-based treatment plans, according to a study published in JAMA Network Open.
“Amitriptyline is commonly used off-label for pain relief, fatigue, sleep disturbance, depression and improving [quality of life] for patients with fibromyalgia,” Hussein M. Farag, PharmD, MSc, PhD, of the department of pharmaceutical economics and policy at Massachusetts College of Pharmacy and Health Sciences, and colleagues wrote. “Despite the