Epigenetics, a term coined by Conrad H. Waddington in the early 1940s, originally described the complex molecular pathways that govern how a genotype manifests as a phenotype. Over time, this definition has evolved to focus on heritable changes in gene activity that occur without altering the DNA sequence itself.
Researchers discuss expanding role of epigenetics in human health and disease
Epigenetics, a term coined by Conrad H. Waddington in the early 1940s, originally described the complex molecular pathways that govern how a genotype manifests as a phenotype. Over time, this definition has evolved to focus on heritable changes in gene activity that occur without altering the DNA sequence itself.