SAN ANTONIO — Plasminogen activator inhibitor-1, or PAI-1, may serve as a biological marker for severe COVID-19, according to data presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.
Susumu Fukahori, MD, PhD, of the University of South Florida, told Healio there are several possible mechanisms behind the higher risk for thrombotic arterial and venous occlusions that occur among patients with COVID-19.
“Among these mechanisms, we were interested in endothelial cell injury in COVID-19. PAI-1 is one of the major mediators produced by endothelial cells