Researchers from the Mitochondrial Medicine Frontier Program at Children’s Hospital of Philadelphia (CHOP) have found that developmental delays associated with Leigh syndrome, the most common pediatric mitochondrial disorder, may occur earlier than previously recognized—even before metabolic stroke and regression—which could provide clinicians with an opportunity for earlier diagnosis and therapeutic interventions. The findings were recently published online by the journal Molecular Genetics and Metabolism.
Researchers show early developmental delays predict poor long-term outcomes in Leigh syndrome patients
Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia (CHOP) have found that developmental delays associated with Leigh syndrome, the most common pediatric mitochondrial disorder, may occur earlier than previously recognized—even before metabolic stroke and regression—which could provide clinicians with an opportunity for earlier diagnosis and therapeutic interventions. The findings were recently published online by the journal Molecular Genetics and Metabolism.