A single therapeutic dose administered on the first day of a drug provocation test could be safe in diagnosing mild nonimmediate reactions to amoxicillin-clavulanic acid, according to a study published in Pediatric Allergy and Immunology.
This single dose would save time because patients would spend less time in the hospital, Giulia Liccioli, MD, of the allergy unit in the department of pediatrics at Meyer Children’s University Hospital in Florence, Italy, and colleagues wrote.
The study involved 354 patients (50.6% boys; mean age at reaction, 4.8 years; standard deviation, ± 3.7 years)