STAT+: Little transparency, lots of waste: NIH funds pediatric research, but many trials results go unpublished

A new analysis found the results of many pediatric clinical trials go unpublished.

The National Institutes of Health provided $362 million in grants for clinical trials that enrolled at least 41,000 children over a recent three-year period — but many results were never published, a new analysis found. The results are a worrisome sign of a lack of transparency that can lead to wasted research funding.

Specifically, just under two-thirds of the 354 trials studied were registered in advance with, the federal database, and just 13% of finished trials were registered within 12 months of completion, according to the analysis, which was published in JAMA. The researchers also estimated that there was just a 54% likelihood  results would be published four years after grants were completed.

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