Findings from a systematic review and meta-analysis of long-term outcomes associated with preterm exposure to antenatal corticosteroids suggest that the timing and dose of administration “should be carefully considered,” researchers said.
The review found that children born extremely preterm who were exposed to a single course of the antenatal corticosteroids betamethasone or dexamethasone had a significantly lower risk for neurodevelopmental impairment. However, children born late preterm or at full term experienced a significantly higher risk for adverse neurocognitive and/or