Located in the mucus layer that lines the gastrointestinal tract, mucins—proteins with attached sugar molecules—play a key role in combating bacterial infection and providing a safe haven to friendly gut bacteria through unknown mechanisms. Although mucin dysregulation leads to metabolic disease and intestinal inflammation, the associated mechanism remains largely unknown.
Study links intestinal glycan modifications to obesity and inflammation
Located in the mucus layer that lines the gastrointestinal tract, mucins—proteins with attached sugar molecules—play a key role in combating bacterial infection and providing a safe haven to friendly gut bacteria through unknown mechanisms. Although mucin dysregulation leads to metabolic disease and intestinal inflammation, the associated mechanism remains largely unknown.