Researchers confirmed that epinephrine can reach therapeutic plasma concentrations via sublingual administration during the second part of the ongoing EPIPHAST study conducted by Aquestive Therapeutics.
“The overall study is designed to understand product characteristics, inform regulators and communicate to health care providers about different factors that could affect epinephrine blood levels, heart rate, blood pressure and safety following administration of sublingual film compared to that following different doses of epinephrine injection, including looking at comparisons that FDA