Substantial individual-level discrepancies exist between measured GFR, eGFR

Researchers identified significant differences in eGFR and measured eGFR on an individual level, according to data published in Annals of Internal Medicine.
“Directly measured glomerular filtration rate (mGFR), the gold standard for assessing GFR, involves injecting a filtration marker and measuring plasma or urinary clearance by serial blood and urine sampling under standardized conditions. As direct GFR measurement is not practical for every patient, GFR is assessed indirectly by the serum concentrations of creatinine in routine clinical practice,” Tariq Shafi, MBBS, MHS, from

Researchers identified significant differences in eGFR and measured eGFR on an individual level, according to data published in Annals of Internal Medicine.
“Directly measured glomerular filtration rate (mGFR), the gold standard for assessing GFR, involves injecting a filtration marker and measuring plasma or urinary clearance by serial blood and urine sampling under standardized conditions. As direct GFR measurement is not practical for every patient, GFR is assessed indirectly by the serum concentrations of creatinine in routine clinical practice,” Tariq Shafi, MBBS, MHS, from