Oral calcium supplementation with or without vitamin D was associated with lower survival and a greater need for aortic valve replacement among older patients with mild to moderate aortic stenosis, researchers reported.
In a large, retrospective analysis with extended follow-up, researchers also found that CV mortality was higher among older patients with mild to moderate aortic stenosis who were supplementing with calcium and did not undergo AVR.
“Strengthened by its large sample size and extended follow-up period, our study suggests that calcium supplementation does not confer any CV