A randomized controlled trial demonstrated a significantly reduced incidence of type 2 diabetes among individuals with metabolic syndrome who received daily metformin with or without a Mediterranean diet intervention.
Cumulative incidence of noncommunicable diseases appeared significantly lower among those who received metformin with or without a Mediterranean diet intervention.
“[Daily metformin] is effective in the prevention of diabetes, but not other NCDs, in people selected on the basis of metabolic syndrome,” Patrizia Pasanisi, MD, director of nutritional and metabolomic