Two formulations of a novel topical isotretinoin ointment formulation were associated with improvements over vehicle in patients with two types of congenital ichthyosis, according to a study.
“Congenital ichthyosis (CI) is being studied because there are no FDA-approved treatments and there is a significant unmet clinical need for this lifetime challenging condition,” Joyce M. C. Teng, MD, PhD, professor of dermatology and pediatrics and director of pediatric dermatology and fellowship training at Stanford University School of Medicine, told Healio. “Although systemic