For severely immunocompromised patients, a bone marrow transplant restores immune defenses and allows them to resume normal life. But after observing the nasopharyngeal system, where the body’s first line of immune defense is deployed, scientists from the Institut Pasteur, Université Paris Cité, Inserm and the Paris Public Hospital Network (AP-HP), in collaboration with the Imagine Institute, demonstrated a failure in the immune mechanisms of some of these patients. The results of this study, published in the journal Blood on February 14, 2022, could pave the way for more effective treatment.
Towards more effective treatments for immunocompromised patients
For severely immunocompromised patients, a bone marrow transplant restores immune defenses and allows them to resume normal life. But after observing the nasopharyngeal system, where the body's first line of immune defense is deployed, scientists from the Institut Pasteur, Université Paris Cité, Inserm and the Paris Public Hospital Network (AP-HP), in collaboration with the Imagine Institute, demonstrated a failure in the immune mechanisms of some of these patients. The results of this study, published in the journal Blood on February 14, 2022, could pave the way for more effective treatment.