A team of researchers at Stanford University has found a significant subset of allele-independent regulatory sites that have multiple causal variants in linkage disequilibrium. In their paper published in the journal Science, the group describes how they applied a massively parallel reporter assay (MPRA) to certain parts of the human genome to look for links between genetic variants and certain human phenotypes.
Using MPRA to determine links between genetic variants and human phenotypes
A team of researchers at Stanford University has found a significant subset of allele-independent regulatory sites that have multiple causal variants in linkage disequilibrium. In their paper published in the journal Science, the group describes how they applied a massively parallel reporter assay (MPRA) to certain parts of the human genome to look for links between genetic variants and certain human phenotypes.